The Animal Clinical Laboratory Services Core provides hematological and clinical chemistry testing as well as multiplexed biomarker immunoassays.

The Department of Biology prints posters for personnel inside the University.

The Biology Plant Growth Facility, a.k.a the Greenhouse. The Department of Biology rents bench space in the Greenhouse to University personnel as well as outside organizations.

Our core provides expertise for qualitative and quantitative analysis of a variety of biomarkers using liquid chromatography and mass spectrometry instrumentation.

The service center enables our biostatisticians to perform the following services for sponsored research on campus: statistical simulations, symbolic mathematic computation, and data analysis, all using specialized software. 

The Gnotobiotic Core at The University of North Carolina at Chapel Hill maintains several inbred and outbred strains of germ-free and gnotobiotic rodents. Our mission is to support animal model and basic research projects of CGIBD investigators and of scientists nationwide.

The Mouse Behavior Core provides investigators within the CIDD and throughout the UNC research community with a wide variety of behavioral tasks for studies in genetic, environmental, and pharmacological models of human disorders, and for preclinical efficacy testing of novel therapeutic agents.

The Research Participant Registry Core provides investigators within the CIDD and approved projects across UNC with assistance recruiting research participants. The Core maintains four registries: autism, fragile X, intellectual and developmental disorders, and local typically developing infants.

Carolina Demography

CPC Research IT Service Center

IBGS at UNC operates at the interface between the UNC School of Medicine and College of Arts & Sciences to support research that works toward a mechanistic understanding of basic biological processes, thereby generating discoveries that fuel the translational research pipeline.

The mission of the Odum Institute for Research in Social Science is to foster groundbreaking social research that improves the lives of people in North Carolina and around the world.

We use automated Fmoc SPPS to make synthetic peptides. We are routinely making 20-30-mer peptides, but also have experience with synthesis of longer sequences, 40-60-mer. Homogeneity is evaluated by mass analysis (MALDI-TOF MS) and analytical HPLC.

The purpose of the Human Pluripotent Cell Core Facility is to provide UNC scientists as well as outside collaborators with the services to successfully conduct basic as well as translational research using human induced pluripotent cells.

The Glass Shop is a full service shop primarily engaged in the design and fabrication of specialized scientific glassware as well as repairs and modifications of existing glassware.

CPAC Core facilitates the development of safe, effective strategies for HIV prevention, treatment, and cure. CPAC Core provides expertise in small molecule drug development to assist investigators in nearly all aspects of HIV pharmacology research.

We provide consultations and collaborations on research studies requiring computational structural biology methods. Analyses available are not limited to the study of static structures, but also include molecular dynamics studies.

We provide a variety of research support services, including access to inpatient and outpatient examination rooms, a staff of highly-skilled research professionals, and specimen processing and short term storage facilities.

Work with a Carolina Data Warehouse analyst to extract and analyze UNC Health patient data. Use i2b2 to explore UNC Health patient data. Collaborate via our Clinical Data Research Networks, ACT, & PCORnet. Use EMERSE & CLARK to search free text clinical notes. Request features to be built in Epic.

We provide expertise, guidance and education on development of a clinical or master protocol for investigator-initiated research. Regulatory consultations are available to guide and support you as you design protocols and navigate through the scientific review process.

The Cystic Fibrosis Foundation, in conjunction with the laboratory of Dr. Jack Riordan and Dr. Martina Gentzsch of the University of North Carolina at Chapel Hill are pleased to offer anti CFTR antibodies to the cystic fibrosis research community.

Health on Wheels is a mobile medical unit program to bring basic health initiatives and opportunities directly to the community. The unit is available to UNC researchers, UNC clinicians and other UNC collaborators.

The mission of the GO Health Center is to expand knowledge and further understand the relationship between oral and systemic health and diseases by conducting clinical dental research, often focusing on specific conditions.

The department’s computing environment includes over 1000 computers, ranging from older systems used for generating network traffic for simulated Internet experiments to state-of-the-art workstations and clusters for graphics- and computer-intensive research.

The OML provides diagnostic clinical microbiology, microbiological research, microbiology training and sterilization monitoring services to both the school and the community of dental practitioners in North Carolina and the surrounding geographic area.

The UNC ESOP NMR Facility serves users from inside and outside the University. The lab has been used to study small molecules and natural products; polymers; and biomolecular structure and dynamics. The facility houses a fully automated 400MR, as well as Inova 500 and Inova 400 spectrometers.

This core provides laboratory analysis of: collagen content, amino acid analysis including collagen specific amino acids, reducible collagen cross-link analysis (including cross-link precursor aldehydes), and non-reducible collagen cross-link analysis (fluorescent and non-fluorescent cross-links).

The Lenti-shRNA Core Facility is premised in Open Biosystems TRC1 shRNA libraries. The libraries are cataloged as a single lentiviral-vector shRNA expression clones directed to +/- 16,000 human and mouse genes. Each gene is targeted by 4 or 5 different shRNAs driven by the U6 promoter.

The UNC CFAR Social and Behavioral Science Research Core seeks to facilitate and support new collaborative HIV-related research that is interdisciplinary and inter-institutional.

Rapid Case Ascertainment is a shared resource at UNC Lineberger Comprehensive Cancer Center that facilitates cancer prevention and control research that requires early contact with patients. RCA is a collaboration between UNC Lineberger and the North Carolina Central Cancer Registry (CCR).

The Biometric Consulting Laboratory, a component of the Department of Biostatistics at the UNC Gillings School of Global Public Health, provides collaborative biostatistical consultation for study design and data analysis for investigators.

The UNC Crystallography Core Facility provides support and infrastructure necessary to enable investigators to initiate and complete a structural biology or structural chemistry project. Services include crystallization, x-ray diffraction data collection, and structure determination and refinement.

The UNC Biomolecular NMR Laboratory was created to support research into the structure and dynamics of biological molecules. The Biomolecular NMR Lab offers a variety of services to academic and industrial users. We are happy to work with users from outside UNCCH to support their research needs.

TPF provides: Tissue Procurement from UNC Hospitals & Rex HC, Blood Procurement & Processing, Quality Assurance/Histopathologic Review, Support of oncology clinical trials, Other biospecimen collection & banking, Tissue Sectioning, Nucleic Acid isolation, Database Management & Tissue Bank Searches.

The mission of the CSCC is to improve public health by coordinating important health research, developing innovative research methodology, and providing practical training in the application of research methods.

The Cecil G. Sheps Center for Health Services Research seeks to improve the health of individuals, families, and populations by understanding the problems, issues, and alternatives in the design and delivery of health care services.

Our Department of Biostatistics is recognized as a worldwide leader in research and practice. Members of our faculty are interested both in the development of statistical methodology and application of biostatistics in applied research.

The Macromolecular Interactions Facility (UNC folks fondly call it the Mac-In-Fac) is a core facility of the University of North Carolina at Chapel Hill. It provides instrumentation & resources for biophysical characterization of biological macromolecules and their interactions with cognate ligands.

The Multidisciplinary Simulation Laboratory, part of the UNC Department of Surgery, provides simulation training in surgical and medical procedures for resident physicians, medical students, physicians, nurses and surgical technologists. The center also hosts medical industry simulation training.

The Division of Pulmonary Diseases and Critical Care Medicine is recognized for its outstanding research programs directed by leading investigators who use a wide range of approaches, including basic, translational, clinical, epidemiological, social and behavioral studies.

The Isotope Geochemistry Lab at UNC Chapel Hill is a fully functional geochemistry laboratory overseen by Dr. Drew Coleman, Dr. Ryan Mills, and Dr. Paul Fullagar (emeritus). University, local, national, and international researchers regularly use the lab for isotope geochemical analyses.

Research partnerships in Africa and Asia are central to the success of the UNC CFAR, whose organizing purpose is to change the course of the epidemic through discovery. Toward this end, we have made extensive, sustained investments in HIV research and training sites in Africa and Asia.

The UNC CFAR Social and Behavioral Science Research Core seeks to facilitate and support new collaborative HIV-related research that is interdisciplinary and inter-institutional.

The purpose of the CFAR Biostatistics Core is to accelerate successful HIV/AIDS research by direct provision of biostatistical support and by arranging mutually beneficial collaborations between CFAR researchers and statistical scientists.

The overarching goal of the Clinical Pharmacology and Analytical Chemistry (CPAC) Core is to facilitate the development of safe, effective strategies for HIV prevention, treatment, and cure. To achieve this goal, the CPAC Core provides expertise in small molecule drug development.

The goal of the UNC CFAR Clinical Core is to enhance all aspects of human HIV research. We provide easy access to comprehensive clinical services, resources and expertise supporting basic science, translational, clinical and public health research.

The Developmental Core provides mentoring support for early stage investigators who are interested in pursuing an HIV research career. We work collaboratively with other CFAR Cores to identify scientific and career mentors as needed, upon request.

The Administrative Core supports and promotes the entire range of basic, clinical, prevention, social, behavioral, and translational HIV research activities throughout the UNC CFAR. It provides the interface with community and advocacy groups, including sponsoring a yearly HIV/AIDS care symposium.

The mucus clearance system of the lung represents a key innate defense system that protects the airway surface against constant exposure to inhaled infectious and noxious particles. Abnormal clearance of mucus is an important contributor to the phenotype of patients with chronic bronchitis (CB).

The Cystic Fibrosis Molecular/Functional Measurement Core is designed to provide services to analyze the efficacy of treatments that target different stages in the pathogenic sequelae of CF disease development.

The Marsico Lung Institute/UNC Cystic Fibrosis Center Animal Models Core is dedicated to providing access and specialized expertise to conduct in vivo studies with animal models (primarily mouse) that provide insights into pulmonary disease pathophysiology and treatment.

Molecular biology has become an indispensable component of modern biological research programs. The Molecular Biology Core was established to provide expertise, equipment, training, and reagents to serve the molecular biology needs for the Marsico Lung Institute/UNC Cystic Fibrosis Center.

Multiple research strategies for treatment of cystic fibrosis (CF) are currently being explored. Translating CF therapeutic strategies from basic research to clinical studies requires the assessment of drug candidates in physiologically relevant assays.

The development and validation of biomarkers that reflect different aspects of cystic fibrosis are of paramount importance to continued efforts to understand disease biology and the development of new therapeutics. Further, translation of basic research ideas into clinical studies is also vital.

The overall objectives of this core are to enhance the productivity of CIDD investigators and the quality of their research. The core can assist IDDRC projects with study design, data management, as well as statistical and bioinformatics analyses.

The Clinical Translational Core includes services to maximize participation of research subjects in IDDRC projects (the Participant Registries), services to support development of image processing tools, multi-modal brain imaging, EEG/ERP and eye tracking.

The Large Animal Models Core was established because in vitro cell culture systems or small animal models have not always translated well to solving human health problems. The core was designed to provide models of digestive disease that are more pathophysiologically similar to humans.

The MMRRC at UNC distributes and cryopreserves scientifically valuable, genetically engineered mouse models of human development and disease to serve the biomedical research community. The MMRRC aims to protect and enhance the mouse models, make them more accessible, and to support research R&R.

Research Electronic Data Capture, or REDCap, is a secure web application that can be used to build and manage case report forms, surveys and other data capture mechanisms for clinical research. We can help get you started, and are always here to help.

Are you interested in learning how you can use PCaP data and biospecimens? Visit our webiste to learn more about enrollment, specimen collection and data sharing for PCaP and HCaP–NC.

The Atomic Absorption Spectrometry Lab provides analysis that is used to determine the levels of arsenate, methylated and other organic forms of arsenic in solutions and/or matrices.

Innovate Carolina is UNC-Chapel Hill’s department for innovation, entrepreneurship and economic development that provides a full-scale hub designed for today’s problem solvers: innovation-minded faculty, students and community partners who use their ingenuity to nudge the world forward.

The Cecil G. Sheps Center for Health Services Research seeks to improve the health of individuals, families, and populations by understanding the problems, issues, and alternatives in the design and delivery of health care services.

Our lab performs various magnetic resonance imaging (MRI) experiments using hyperpolarized Xenon (HPXe) gas to look at the lungs of mouse models of cystic fibrosis.

Health Information Services provides data sets through the Perinatal Research Service Center (PRSC). Currently we have a complete integrated data set for Deliveries, and our plan is to develop other perinatal domains that include prenatal, postpartum, lactation, NICU, ICU, diabetes, & hypertension.

Abacus is a program evaluation and research consultancy committed to amplifying our clients’ impact and effectiveness. Our work fosters innovation and advances equity in research and health outcomes through evaluation.

PRU provides outstanding technical services and a seamless approach in working with the IACUC, DCM, and other core facilities on campus for labs that utilize small laboratory animals in their research. We offer technical expertise with small laboratory animal models for reproducibility of research.