Welcome!
The UNC Metabolomics and Proteomics (MAP) Core facility provides services for the analysis of proteins from tissues, cells or other biological samples. We are available to the UNC community, as well as external customers worldwide. We’re committed to educating students and researchers in the field of proteomics and will work with you from initial experimental design through publication.
We offer an array of sample preparation and instrumentation services, as well as method development and in-depth consultation to help researchers optimize their experimental design. The facility is equipped with four state-of-the-art systems: a Sciex 5800 MALDI-TOF/TOF, a Thermo QExactive HF, a Thermo QExactive HF Biopharma and a Thermo Fusion Lumos Tribrid. In addition to the mass spectrometers, we have three Thermo Easy nLC 1200s and a 908 Devices ZipChip capillary electrophoresis device for up-front separation. We have an Agilent 1260 Infinity II HPLC for offline peptide fractionation. We offer several services including: protein identification, protein characterization, phosphoproteomics, large-scale proteomic profiling, intact mass analysis, and protein-protein interaction analyses. We can perform these services quantitatively using labeled (SILAC or TMT10plex/16plex) or label-free approaches. Comprehensive data analysis is provided through a variety of database search engines (Mascot, Sequest) and software packages including Protein Pilot, Proteome Discoverer, MaxQuant, Byos, and Scaffold. We can also aid in bioinformatics analysis using Ingenuity Pathway Analysis (IPA), David, and Perseus.
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Laura Herring, PhD | Facility Director
Office: 4078 Genetic Medicine Building
Phone: 919-966-4681
Email: laura_herring@med.unc.edu
| Hours | Building | Address | |
| 9am-5pm | Glaxo Location (Wet labs, Staff offices) | 111 Glaxo Building | Chapel Hill, NC 27599 |
| 9am-5pm | GMB Location (Mass specs and Directors office) | 4100H Genetic Medicine Building | Chapel Hill, NC 27599 |
Please visit our website for more information: proteomics.unc.edu
| Name | Role | Phone | Location | |
|---|---|---|---|---|
| Laura Herring, PhD |
Facility Director
|
919-966-4681
|
laura_herring@med.unc.edu
|
4078 Genetic Medicine Building
|
| Lee Graves, PhD |
Faculty Director
|
919-966-0915
|
lmg@med.unc.edu
|
4111 Genetic Medicine Building
|
| Allie Mills, PhD |
Postdoctoral Research Associate
|
allie.mills@unc.edu
|
110 Glaxo Building
|
|
| Natalie Barker |
Research Associate
|
natalie_barker@med.unc.edu
|
111 Glaxo Building
|
