The Advanced Translational Pharmacology and Analytical Chemistry (ATPAC) Core Lab

Overview of Services

The Advanced Translational Pharmacology and Analytical Chemistry (ATPAC) core lab consists of the Analytical Chemistry and Pharmacology Core (ACPC) lab and the Translational Oncology and Nanoparticle Drug Development Initiative (TONDDI) lab. Lab activities occur in the UNC Eshelman School of Pharmacy, the UNC Lineberger Comprehensive Cancer Center, and the Carolina Institute of Nanomedicine.

The ATPAC core lab uses analytical chemistry and pharmacologic infrastructure to support the translational development of drugs, anticancer agents, carrier-mediated agents and biologics. The lab provides expertise in translational drug development, analytical chemistry, pharmacology [pharmacokinetic (PK) and pharmacodynamic (PD); efficacy and toxicity], and biomarker studies,

The ATPAC core lab provides bioanalytical services including LC-MS assay development, validation and analysis of samples to quantify a wide variety of drugs, ranging from small molecule therapeutics to complex drugs such as monoclonal antibodies, drug conjugates and polymers. The lab is equipped to support your entire project: formulation development and CMC studies, assistance in PK/PD study design, LC-MS/MS or ICP-MS assay development, quantification of drugs from biological samples, PK/PD analysis and report generation.

Leadership

Location and hours of operation

Links and Resources

1. https://pharmacy.unc.edu/research/faculty-labs/atpac/

Contacts