The Clinical Genomic Analysis (GENYSIS) Core

Overview of Services

The Clinical Genomic Analysis (GENYSIS) Core is a research service that collaborates with the BioSpecimen Processing (BSP) facility, the High-Throughput Sequencing Facility (HTSF), and the McLendon Molecular Genetics Laboratory (MGL) to provide clinical researchers with four main services:

1. Bioinformatics – performing human genome alignment of sequence data generated from the HTSF (or other sequencing center) and variant calling via a custom in-house pipeline.
2. Variant analysis – correlation with participant phenotypic data, and analysis of called variants by highly trained staff. Reportable variants are discussed at a weekly meeting attended by MDs, PhDs, and genetic counselors (GCs).
3. Clinical reporting – generation of a clinical-grade test report for the variants clinically confirmed in the MGL that can also be uploaded to Epic if the participant is a UNC patient.
4. Post-test services - assisting the study, clinician, participants, and their family, including reviewing results, providing educational resources, and identifying appropriate clinical follow-up.

Request a free consultation to discuss the needs of your project.


Tam P. Sneddon, PhD Director
Kim Foss, MS, CGC Assistant Director
Bradford Powell, MD, PhD Faculty Director

Location and hours of operation

Hours Location

Monday - Friday 

8AM - 5PM

Genetic Medicine Building (GMB)

120 Mason Farm Road

Chapel Hill, NC, 27599

Links and Resources


Name Role Phone Email Location
GENYSIS Core (Dr. Tam P. Sneddon)

(919) 966-4676