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Pathology Services Core

Overview of Services

The Pathology Services Core provides high quality, comprehensive pathology services for pre-clinical and clinical studies. Services: Histopathology including tissue processing, routine frozen and paraffin slide preparation, Tissue MicroArrays, immunohistochemistry and in situ hybridization (ISH, FISH), RNAScope, digital pathology and digital spatial profiling (protein & RNA). The PSC has access to UNC-CH's tissue archive and faciliates and coordinates clinical studies. Equipment and Technology: GeoMx Digital Spatial Profiler (NanoString), Xenium, CytAssist (10x Genomics), PhenoCycler (Akoya Biosciences), Bond III & Rx Autostainers, Ventana Stainer, XL Autostainer, Image Analysis with Halo AI, Slide Scanning with a Versa 200, ScanScope AT2 and Scan Scope FL scanners, Tissue Arrayers, Leica Processors, Embedding Stations, Microtomes, Cassette & Slide Labelers.

Please note this PSC policy: Multiple sections per slide from same or multiple blocks will be charged per section. 

To submit samples to the PSC:

1) Submit a request in ilabs.

2) Label all sample containers with PI/Submittor name and ILabs Request Number (PSC-XX-XXX).

3) Brinkhous-Bullitt (160 N Medical Drive); 9th Floor: Submit samples on PSC table outside the elevators (left hand side).

4) Email Gaby with drop-off confirmation at gdelacruz@med.unc.edu. 

 

Leadership

Gabriela De La Cruz, BS, MPM (C/O ’25)

Facility Director (primary contact)

gdelacruz@med.unc.edu

Lauren Ralph, HTL (ASPC)

Facility Manager

lauren_ralph@med.unc.edu

Charlene Santos, CMAR, MBA

Operations Director

csantos@unc.edu

Rani Sellers, PhD, DVM, DACVP

Faculty Director-PreClinical Toxicology

rsselle@email.unc.edu

Sara Wobker, MD, MPH

Faculty Advisor-Clinical

sara_wobker@med.unc.edu

Hannah Atkins, PhD, DVM

Faculty Advisor-Digital Pathology

hannah_atkins@med.unc.edu

 

Location and hours of operation

Hours Location

Monday-Friday    

7:00AM-5:00PM

160 Medical Drive

9th Floor Brinkhous Bullit Building

Chapel Hill, NC, 27599

Links and Resources

  1. https://unclineberger.org/pathologyservices/

Contacts

Name Role Phone Email Location
Gaby De la Cruz
Facility Director
 

 
gdelacruz@med.unc.edu
 
BBB 919
 
Lauren Ralph
Facility Manager
 

 
lauren_ralph@med.unc.edu
 
BBB 919