Welcome!
Formerly known as the NORC Animal Metabolism Phenotyping Core, the metabolic phenotyping component of the new Genomics and Energy Metabolism (GEM) Core provides contemporary phenotyping techniques for metabolism and energy balance in mouse models of nutrition and disease.
GEM Core: Metabolic Phenotyping offers technical support and expertise for measuring traits related to metabolism in mouse models of obesity and nutritionally relevant disease. With locations in Chapel Hill and Kannapolis, the Core provides access to state-of-the-art methods, equipment, and populations to support high quality and high throughput phenotyping of energy balance components in mice.
Please submit service requests at least 2 weeks ahead of your preferred project start date to allow for scheduling.
Core staff will respond to your requests with a confirmation or alternative options within one business day.
Our productivity and effectiveness as a Center is measured in part by the citation of our grant in your published work.
Please acknowledge National Institutes of Health grant DK056350 in all publications resulting from the use of our services.
Raz Shaikh, PhD
Core Director - Chapel Hill
phone: (919) 843-4348
email: shaikhsa@email.unc.edu
Isis Trujillo-Gonzalez, PhD
Core Co-Director - UNC Nutrition Research Institute
phone: (704) 250-5041
email: isis_trujillo@unc.edu
| Hours | Locations |
|
8 AM - 5 PM
Monday - Friday |
Core Manager Office
|
| Name | Role | Phone | Location | |
|---|---|---|---|---|
| Raz Shaikh, PhD |
Director - Chapel Hill
|
(919) 843-4348
|
shaikhsa@email.unc.edu
|
Chapel Hill, NC
|
| Isis Trujillo, PhD |
Co-Director - Nutrition Research Institute
|
(704) 250-5041
|
isis_trujillo@unc.edu
|
Kannapolis, NC
|
| Erika Rezeli |
Manager - Seahorse Services
|
(919) 966-5590
|
erika@unc.edu
|
Chapel Hill, NC
|
| Christelle Douillet |
Manager
|
919-525-1926
|
christelle_douillet@med.unc.edu
|
Chapel Hill, NC
|
| Service list |
| ► Chapel Hill Analysis Services (7) | |||
| Name | Description | Price | |
|---|---|---|---|
| MRI (Analysis of Body Composition) - Chapel Hill |
MRI scanner technology is used is evaluate whole body composition (including fat, lean tissue and water) in live mice without anesthesia. This analysis also includes measurements for whole tissues and tissue biopsies. The GEM Core: Metabolic Phenotyping has adjusted the rate of EchoMRI services to $15 per mouse. The rate increase is attributed to increased operational costs and will bring core services into alignment with guidance provided by The Office of Sponsored Research. Priced Per Mouse
|
Internal UNC-CH
$17.00
Sample
External $35.00 Sample |
|
| Calorimetry (Analysis of Energy Expenditure/Food & Drink Consumption) - Chapel Hill |
 The calorimetry instrumentation (TSE systems) is used to evaluate and interpret energy expenditure in mice. The system measures O2 consumption & CO2 production, respiratory exchange rate, and energy expenditure in the home cage environment. The indirect calorimetry can also evaluate and interpret energy expenditure in 3-D (X, Y and Z dimension) via light beams for up to 10-days using intervals between 1 to 60 minutes in the home cage environment.
Priced Per Mouse/day
|
Internal UNC-CH
$34.00
Sample
External $58.00 Sample |
|
| Voluntary Running Wheel (Analysis of Voluntary Exercise) |
Using the voluntary running wheel, daily summary measurements including total daily revolutions, time spent running (i.e., cumulative 1-minute intervals in which at least one revolution was recorded), average speed (total revolutions / time spent running) and maximum speed (highest number of revolutions in any one-minute interval within a 24 hour period) are recorded and analyzed in mice. Priced Per Mouse
|
Internal UNC-CH
$51.00
Sample
External $83.00 Sample |
|
| Metabolic Cages for Collection of Urine and Feces - Chapel Hill |
This custom system combines 15 metabolic cages (Hatteras Instruments) and a cooling unit. The cooling unit keeps the urine samples at or below 45F during the collection. Different from traditional non-chilled metabolic cages, this system will prevent bacterial multiplication, improve sample quality and increase the sample shelf life. Useful for studies on the effects of drug therapies, urinary protein excretion, renal function studies, evaluation of standard or intervened metabolic function, and daily food and water intake. Suggested collection period, 6-24 hours. Priced Per Mouse
|
Internal UNC-CH
$12.00
Sample
External $27.00 Sample |
|
| Treadmill (Analysis of Mouse Exercise Performance Measurement) |
The Exer-3/6 treadmill is a general purpose animal exerciser. This analysis includes 3 adaptations and one-maximal performance measurement. These tests help to examine the metabolic parameters in mice using speed, acceleration, and distance traveled as measures. The data is recorded and analyzed by the core using statistical Exer-3/6 software. Priced Per Mouse
|
Internal UNC-CH
$39.00
Sample
External $79.00 Sample |
|
| Study Design and Data Interpretation - Chapel Hill |
Expertise provided on study design, data interpretation, quality control, and analysis methods. |
Internal UNC-CH
$96.00
/hr
External $149.00 /hr |
|
| Animal Care, Handling, Sample Processing and Oversight |
Mouse breeding, colony management, sample handling, restrain and care, and other laboratory |
Internal UNC-CH
$30.00
/hr
External $91.00 /hr |
|
